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Applications note #139 “AFM and Raman Spectroscopy – Correlated Imaging and Tip Enhanced Raman Scattering”: · Educates about AFM and Raman spectroscopy and explains the benefits of combining them in a straightforward way. · Highlights Bruker’s unique offerings in the field, the Innova-IRIS, Catalyst-IRIS, and ICON
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Correlated Imaging & Latest TERS Advances
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It is now well established that measuring ex vivo the mechanical properties of living cells can be a good indicator of the health of the organism from which they were extracted. Atomic force microscopy (AFM) is a powerful investigation and diagnostic tool, especially in force mode. Nevertheless, force spectroscopy suffers from several limitations, including
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Brochure describing Bruker's BioScope Catalyst Perfusing Stage Incubator accessory.
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The Veeco Bioscope Catalyst - AFM with Inverted Optical Microscope Mickael Febvre from Veeco takes us for a tour of the Bioscope Catalyst, which is an atomic force microscope (AFM) with an inverted optical microscope. The system is suited to biological applications. Mickael also shows us through the software package and demonstrates a new detection
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Mechanical properties of cells are determined by the dynamic behavior of the cytoskeleton and physical interactions with the environment. The cytoskeleton, composed of actin filaments, intermediate filaments, and microtubules, is vital for numerous key cellular processes, such as cell division, vesicle trafficking, cell contraction, cell motility, and
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Atomic force microscopy (AFM) has opened exciting new avenues in microbiology and biophysics for probing microbial cells. The unprecedented capabilities of AFM can be summarized as follows: i) imaging surface topography with nanometer lateral resolution and under physiological conditions; ii) measuring local physical properties such as adhesion forces
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AFM has contributed to ground-breaking research in the investigation of DNA, proteins, and cells in biological studies; structure and component distribution in polymer science; piconewton force interactions and surfactant behavior in colloid science; and physical/ mechanical properties and fabrication variables in the material sciences. Pharmaceutical
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Microscopic evaluation is important for the design and evaluation of a pharmaceutical product after the steps in the drug formulation process. Since atomic force microscopy (AFM) provides the ability to directly investigate surface structure at nanometer-to-subangstrom resolution in ambient and liquid environments, it has been applied to a wide range
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HarmoniX Nanoscale Material Property Mapping mode with fluorescence microscopy is used to probe the surface characteristics of tissues isolated from the wheat grain. The resulting data provides new insights into this essential ingredient in human nutrition.