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Alex, The five ROI limit is intentional. Apparently these are memory intensive. Remember though that the ROI settings are saved when you save the MIRO canvas. So you can always save your current ROI settings, then modify and save again under a different filename. You don't need to recreate anything. Also remember that you can have up to 8 layers
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July 2011, Issue 02 Research Spotlight The BioScope Catalyst AFM and Fluorescence Techniques Enable Researchers to Learn More about Cell Mechanics and Functions By: Andreas Holloschi, Ph.D. Andreas Holloschi began a research collaboration with the Bruker team two years ago, which rapidly led to promising results in the field of neurodegenerative diseases
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Webinar Content 26. January 2011 High Resolution Imaging with the BioScope Catalyst AFM provides many advantages for high resolution studies of single biomolecules. With a high signal to noise ratio, the elimination of the need for coating, staining, or crystallization of a sample, and the ability to operate in fluid, AFM facilitates the study of biomolecules
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What is MIRO?
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Mechanical properties of cells are determined by the dynamic behavior of the cytoskeleton and physical interactions with the environment. The cytoskeleton, composed of actin filaments, intermediate filaments, and microtubules, is vital for numerous key cellular processes, such as cell division, vesicle trafficking, cell contraction, cell motility, and
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Multi-Modal Imaging and Measurements Correlating Optical and Atomic Force Microscopy
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HarmoniX Nanoscale Material Property Mapping mode with fluorescence microscopy is used to probe the surface characteristics of tissues isolated from the wheat grain. The resulting data provides new insights into this essential ingredient in human nutrition.
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The new MIRO 2.0 (Microscope Image Registration and Overlay) software completes the compromise-free integration of optical and atomic force microscopy (AFM) by providing the tools necessary to control the combined optical/AFM Bioscope™ Catalyst TM system and analyze the resulting data. MIRO 2.0 allows AFM and optical data to be overlaid on the
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The best research instruments not only acquire the intended data, but actually increase productivity. Bruker’s BioScope Catalyst Atomic Force Microscope (AFM) accelerates innovative research by reducing the time and effort needed to combine the proven techniques of light microscopy with the unique benefits of atomic force microscopy.
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In the following study, we demonstrate the power of combining atomic force microscopy AFM and fluorescence microscopy techniques to probe real-time, in-situ effects of two highly specific drugs that are able to disrupt different cytoskeleton networks inside living cells. Using Veeco Multiple Image Registration Overlay (MIRO) software and the new Bioscope