The Nanoscale World

Postdoc applicant

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Posted: Fri, Feb 3 2012 8:06 AM

Please find below Celine Heu's resume. Celine worked with me on QNM testing on living cells and although she has a pure biology background, she would be interested in discovering more about AFM. If you happen to have a postdoc position in your lab and think this profile might fit, feel free to contact me for further details or Celine for a face-to-face discussion.

Alex. 

HEU Céline

17 rue des anémones

25660 Saône

06.32.91.19.83

celine.heu59@gmail.com

Driving licence

26 years

 

 

EDUCATION

 

2006-2008

Post Graduate Degree following my Master in proteomic

 

Université des Sciences et Technologies de Lille

2006

3 years university degree in Cell biology and physiology

 

Université des Sciences et Technologies de Lille

2003

A-levels Scientific pass with distinction (80 % upwards)

 

Lycée Paul Hazard Armentières.

 

PROFESSIONNAL EXPERIENCE

 

October 2008

– today

 

PhD: Biological barrier aging: Morphological and functional characterization of an in vitro chemically-induced oxidative stress consequences.

Cell culture, Flow cytometry (FC500, Beckman Coulter), Fluorescence confocal microscopy (FV1000, Olympus), Atomic Force Microscopy (Nanoscope II, Brucker – Bioscope Catalyst, Brucker),Cell fractionation, 2D gel electrophoresis, 2D HPLC (PF2D, Beckman Coulter), Mass Spectrometry (MALDI/TOF/TOF ultraflex, Bruker)

 

- Cell Biology laboratory, UFR Sciences Médicales et Pharmaceutiques, Université de Franche Comté, Besançon

- CLInical Proteomic Platform (CLIPP), FEMTO-ST institute, Besançon

 

February - July 2008

Development Ingeneer Intern: Epitope Characterization by mass spectrometry (MALDI/TOF biflex IV (Bruker), Orbitrap LTQ XL (Thermo Scientific), development of in gel and solution proteolytc digestion)

 

Direction des Sciences du vivant, SBTN, CEA Valrho, Bagnols-sur-Cèze

 

June – august 2007

Technician Intern in Proteomic: Mass Spectrometry Imaging MALDI/TOF

 

Laboratoire de Neuroimmunologie des annélides, FRE CNRS 2933, Université des Sciences et Technologies de Lille

 

June – july 2006

Technician Intern in Cellular Biology: Cell culture and transformation, western Blot

 

Laboratoire d’immunopathologie cellulare des maladies infectieuses, UMR 8527 CNRS, Institut de Biologie de Lille

 

Oct 2005 - june 2007

Reception officer: Student welcoming and helping (4 hours a week)

 

SUAIO – Université des Sciences et Technologies de Lille

 

August 2005 et 2006

Telephonist

 

Lille Métropole Habitat Agence de Villeneuve d’Ascq.

 

June – july 2005

Technician Assistant Intern in Bacteriology: Autopsy, sampling, bacterial culture, ELISA.

 

Laboratoire Départemental Public à Villeneuve d’Ascq.

 

 

 

 



COMMUNICATIONS

 

Scientific papers:

 

Heu C, Elie-Caille C, Mougey V, Launay S, Nicod L. A step further towards glyphosate induced epidermal cell death: involvement of mitochondrial and oxidative mechanisms, Environmental Toxicology and Pharmacology (Submit)

 

Heu C, Berquand A, Elie-Caille C, Nicod L.Glyphosate-induced stiffening of HaCaT keratinocytes, a PeakForce tapping study on living cells, Journal of Structural Biology (minor revisions)

 

Elie-Caille C, Heu C, Guyon C, Nicod L. Morphological damages of a glyphosate-treated human keratinocyte cell line revealed by a micro- to nanoscale microscopic investigation, Cell Biology and Toxicology 26 (2010) 331-339

 

Oral communications and posters:

 

Heu C, Lucchi G, Berquand A, Ducoroy P, Elie-Caille C and Nicod L. Proteomic mapping of glyphosate-treated human keratinocytes cell line using two-dimensional Electrophoresis. Spectrométrie de Masse et Analyse Protéomique (SMAP) Avignon, 19-22 septembre 2011

 

Heu C, Berquand A, Nicod L and Elie-Caille C. Characterizing the glyphosate-induced epidermal cell mechanical properties using the QFM-based Peak Force QNM Technology. AFM Biomed, Paris, 23-27 aout 2011

Heu C, Elie-Caille C, Mougey V, Launay S and Nicod L. Involvement of mitochondrial and oxidative mechanisms in glyphosate-induced epidermal cell death. 4th International Symposium of Nutrition, Oxygen Biology and Medicine -- "Free Radicals, Nutrition and Aging: from fundamental aspects to clinical applications", Paris, 15-17 juin 2011

Heu C, Elie-Caille C and Nicod L. Implication des mécanismes mitochondriaux et oxydants
dans la mort des cellules épidermiques induite par le glyphosate
Congrès Annuel de Recherche Dermatologique (CARD), Besançon, 23-24 juin2011


Heu C, Elie-Caille C and Nicod L. Cell Imaging connected with protein mapping to investigate glyphosate-induced toxicity on human keratinocytes. International Symposium of Biophysics and imaging of the skin (ISBS), "From surface to Deepness", Besançon, 9-12 sept 2009


Elie-Caille C, Heu C, Lesniewska E and Nicod L. Cell nanosensing connected with protein mapping to explore environmental deleterious effects on the skin.
Nanobio Europe Minatec, Grenoble, 16-18 juil 2009


Heu C, Nicod L, Rossignol J, Lesniewska E and Elie-Caille C. Caractérisation morphologique et fonctionnelle des conséquences du stress oxydant induit chimiquement sur  un modèle cellulaire cutané /in vitro/. Forum Microscopies à sondes locales, Neufchâtel-Hardelot, 16-20 mars 2009

 

LANGUAGE / COMPUTING


 

English (TOEIC score 870 in 2011);

German and Dutch.

Microsoft Word, Excel, power point.

 

 

Progenesis Samespot (NonLinear dynamics)

Biotools, Flex Analysis and Proteinscape (Brucker Daltonics)

CXP cytometer (Beckman Coulter)


INTERESTS

 

Clarinettist for 16 years, Violonist for 5 years

Dance for 8 years

 

REFEREES

 

Laurence NICOD, Professeur, +33 (0)3 81 66 55 57 - laurence.nicod@univ-fcomte.fr

Alexandre Berquand, PhD, +49 (0) 1743339462 - Alexandre.Berquand@bruker-nano.com

Jean Armengaud, PhD, +33 (0)4 66 79 68 02 – jean.armengaud@cea.fr

 

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