The Nanoscale World

Practical Advice on the Determination of Cantilever Spring Constants


Mon, Jan 4 2010

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Practical Advice on the Determination of Cantilever Spring Constants

Atomic force microscopy (AFM) is being used in a great variety of force measurement applications, including investigating the unfolding pathways of native membrane proteins, probing the structure of single polysaccharide molecules, and monitoring the response of living cells to biochemical stimuli. All of these techniques rely on the accurate determination of the cantilever spring constant in order to yield quantitative results.

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