The Nanoscale World

Nanofilaments on glioblastoma exosomes revealed by peak force microscopy


posted by Shivani Sharma
Thu, Jan 9 2014

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Nanofilaments on glioblastoma exosomes revealed by peak force microscopy

Nanofilaments on glioblastoma exosomes revealed by peak force microscopy

Shivani Sharma, Kingshuk Das, JungReem Woo and James K. Gimzewski
e-mail: sharmas@ucla.edu
e-mail: gim@chem.ucla.edu
 
Abstract
Exosomes are sub-100 nm extracellular vesicles secreted by normal and cancer cells. We present a high-resolution structure of previously unidentified nanofilaments on glioblastoma-derived exosomes, using nanoscale peak force imaging. These stiff, adhesive, trypsin- and RNAse-resistant surface nanofilaments add a new dimension to the current structural knowledge of exosome-mediated intercellular communication.

Comments

Shivani Sharma wrote re: Nanofilaments on glioblastoma exosomes revealed by peak force microscopy
on Thu, Jan 9 2014 10:40 AM

Nanofilaments on glioblastoma exosomes revealed by peak force microscopy

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