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In addition to its high resolution imaging capabilities, atomic force microscopy (AFM) has emerged as a powerful tool for measuring both the nanomechanical properties and interaction forces of biomolecular complexes. While the majority of these types of AFM studies have been conducted on isolated molecules, for true biological relevance these investigations
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Atomic Force Microscopy (AFM) operates by scanning a sharp tip, supported on a sensitive force-sensing cantilever, over the sample and thereby producing a three-dimensional image of the surface. As the tip scans across the samples, changes in the interactions with the surface alter the vertical deflection of the tip. These changes in deflection are
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Atomic force microscopy (AFM) is used to investigate structural aspects of cataract formation. High-resolution imaging of native lens membranes and the constitutive protein components was achieved using a customized Veeco atomic force microscope.