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Alex, The five ROI limit is intentional. Apparently these are memory intensive. Remember though that the ROI settings are saved when you save the MIRO canvas. So you can always save your current ROI settings, then modify and save again under a different filename. You don't need to recreate anything...
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July 2011, Issue 02 Research Spotlight The BioScope Catalyst AFM and Fluorescence Techniques Enable Researchers to Learn More about Cell Mechanics and Functions By: Andreas Holloschi, Ph.D. Andreas Holloschi began a research collaboration with the Bruker team two years ago, which rapidly led to promising...
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Webinar Content 26. January 2011 High Resolution Imaging with the BioScope Catalyst AFM provides many advantages for high resolution studies of single biomolecules. With a high signal to noise ratio, the elimination of the need for coating, staining, or crystallization of a sample, and the ability to...
Posted to
Events
on Wed, Jan 12 2011
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What is MIRO?
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Mechanical properties of cells are determined by the dynamic behavior of the cytoskeleton and physical interactions with the environment. The cytoskeleton, composed of actin filaments, intermediate filaments, and microtubules, is vital for numerous key cellular processes, such as cell division, vesicle...
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Multi-Modal Imaging and Measurements Correlating Optical and Atomic Force Microscopy
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Application Notes
by
SeanHand
on Tue, Dec 29 2009
Filed under: MIRO, Cells, TappingMode, Force Curve, OTESPA, BioScope II
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HarmoniX Nanoscale Material Property Mapping mode with fluorescence microscopy is used to probe the surface characteristics of tissues isolated from the wheat grain. The resulting data provides new insights into this essential ingredient in human nutrition.
Posted to
Application Notes
by
SeanHand
on Tue, Dec 29 2009
Filed under: MIRO, Catalyst, Dissipation, Stiffness, Adhesion, Peak Force, Phase, HMX, NanoScope V, HarmoniX, Point and Shoot, HMX-S
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The new MIRO 2.0 (Microscope Image Registration and Overlay) software completes the compromise-free integration of optical and atomic force microscopy (AFM) by providing the tools necessary to control the combined optical/AFM Bioscope™ Catalyst TM system and analyze the resulting data. MIRO 2.0...
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The best research instruments not only acquire the intended data, but actually increase productivity. Bruker’s BioScope Catalyst Atomic Force Microscope (AFM) accelerates innovative research by reducing the time and effort needed to combine the proven techniques of light microscopy with the unique...
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Brochures & Data Sheets
by
Stephen Minne
on Wed, Dec 16 2009
Filed under: Brochure, MIRO, BioScope, Catalyst, Peak Force Tapping, 8.10, ScanAsyst, PeakForce QNM, TappingMode
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In the following study, we demonstrate the power of combining atomic force microscopy AFM and fluorescence microscopy techniques to probe real-time, in-situ effects of two highly specific drugs that are able to disrupt different cytoskeleton networks inside living cells. Using Veeco Multiple Image Registration...
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There is great interest in unraveling action mechanisms of key enzymes in biological processes. In many cases, insight on such molecular events can be derived from conventional biophysical analyses of isolated enzymes and their substrates or protein partners. For example, members of the matrix metalloproteinases...